hsa-miR-30a

ncRNA information

ncRNA name

hsa-miR-30a

Specific or universal ncRNAs

Specific ncRNAs

Class

MicroRNA

Biomarker

No

Biomarker application

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Gastric Cancer

Cancer site

Stomach

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil/Cisplatin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

MiR-30a can decrease multidrug resistance (MDR) of gastric cancer cells. It is also an important miRNA modulating EMT of the cancer cells.

Tissue resource

gastric cancer tissues

human gastric cancer cell lines SGC-7901

human gastric cancer cisplatin-resistant cell lines SGC-7901/DDP

Experiment

qRT-PCR,Western blot


Institute

First Hospital of Hebei Medical University

KeyGEN Biotechnology Company

Country

China

Continent

Asia