GAS5

ncRNA information

ncRNA name

GAS5

Specific or universal ncRNAs

Universal ncRNAs

Class

Long noncoding RNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

Not available

Cancer information

Cancer name

Bladder Transitional Cell Carcinoma

Cancer site

Bladder

Treatment information

Treatment type

Chemotherapy

Drug

Doxorubicin

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

82

Male patients

54

Female patients

28

Age range and number

Not available

Research information

PMID

Description

GAS5 enhancement reduced the chemotherapy resistance to doxorubicin.

Tissue resource

bladder transitional cell carcinoma and normal bladder tissues

human bladder transitional cell carcinoma cell lines T24

human bladder transitional cell carcinoma cell lines J82

hhuman fetal bladder tissue derived cell lines CCC-HB-2

Experiment

qRT-PCR,Western blot


Institute

Shengjing Hospital of China Medical University

China Academy of Chinese Medical Sciences

Country

China

Continent

Asia