Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
GAS5
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
Not available
Cancer name
Bladder Transitional Cell Carcinoma
Cancer site
Bladder
Treatment type
Chemotherapy
Drug
Doxorubicin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
82
Male patients
54
Female patients
28
Age range and number
Not available
PMID
Description
GAS5 enhancement reduced the chemotherapy resistance to doxorubicin.
Tissue resource
bladder transitional cell carcinoma and normal bladder tissues
human bladder transitional cell carcinoma cell lines T24
human bladder transitional cell carcinoma cell lines J82
hhuman fetal bladder tissue derived cell lines CCC-HB-2
Experiment
qRT-PCR,Western blot
Institute
Shengjing Hospital of China Medical University
China Academy of Chinese Medical Sciences
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.