hsa-miR-365

ncRNA information

ncRNA name

hsa-miR-365

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

GALNT4

Cancer information

Cancer name

Breast Cancer

Cancer site

Breast

Treatment information

Treatment type

Chemotherapy

Drug

5-Fluorouracil

Impact of wild-type ncRNA on chemotherapy resistance

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Down

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Not available

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

Description

Overexpression of microRNA-365 inhibits breast cancer cell growth and chemo-resistance through GALNT4.

Tissue resource

breast cancer and adjacent normal breast tissues

human breast cancer cell lines MCF740

human breast cancer cell lines BT47441

human breast cancer cell lines HCC3842

human breast cancer cell lines HTB-12141

normal human breast tissue cell lines Hs861.T

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

Shidong Hospital

American Type Culture Collection

Country

China

USA

Continent

Asia

Amercia