Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-365
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
GALNT4
Cancer name
Breast Cancer
Cancer site
Breast
Treatment type
Chemotherapy
Drug
5-Fluorouracil
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Overexpression of microRNA-365 inhibits breast cancer cell growth and chemo-resistance through GALNT4.
Tissue resource
breast cancer and adjacent normal breast tissues
human breast cancer cell lines MCF740
human breast cancer cell lines BT47441
human breast cancer cell lines HCC3842
human breast cancer cell lines HTB-12141
normal human breast tissue cell lines Hs861.T
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
Shidong Hospital
American Type Culture Collection
Country
China
USA
Continent
Asia
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.