Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-210
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
ABCC5
Cancer name
Pancreatic Ductal Adenocarcinoma
Cancer site
Pancreas
Treatment type
Chemotherapy
Drug
Gemcitabine
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
Down
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
MicroRNA-210 overexpression inhibits tumor growth and potentially reverses gemcitabine resistance in pancreatic cancer.
Tissue resource
ancreatic cancer and normal pancreas tissues
human pancreatic ductal adenocarcinoma cell lines BxPC-3
human pancreatic ductal adenocarcinoma cell lines AsPC-1
human pancreatic ductal adenocarcinoma cell lines MIA-PaCa2
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
University of Heidelberg
American Type Culture Collection
Country
Germany
USA
Continent
Europea
Amercia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.