Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
hsa-miR-26b
Specific or universal ncRNAs
Universal ncRNAs
Class
MicroRNA
Biomarker
No
Biomarker application
Upstream regulatory factors
Not available
Downstream target
JAG1
Cancer name
Nasopharyngeal Carcinoma
Cancer site
Nasopharynx
Treatment type
Chemotherapy
Drug
Cisplatin
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Up
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Not available
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
Down-regulation of miR-26b induces cisplatin resistance in nasopharyngeal carcinoma by repressing JAG1.
Tissue resource
nasopharyngeal carcinoma samples and normal tissues
nasopharyngeal cancer cell lines CNE2
nasopharyngeal cancer cell lines HNE1
nasopharyngeal cancer cisplatin-resistant cell lines HNE1/DDP
Experiment
qRT-PCR,Western blot,Dual-luciferase reporter assay
Institute
Shandong Provincial Hospital Affiliated to Shandong University
the Central Laboratory of Xiangya School of Medicine
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.