hsa-miR-31

ncRNA information

ncRNA name

hsa-miR-31

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factors

Not available

Downstream target

NDRG3

Cancer information

Cancer name

Hepatocellular Carcinoma

Cancer site

Liver

Treatment information

Treatment type

Chemotherapy

Drug

Adriamycin

Impact of wild-type ncRNA on chemotherapy resistance

Down

Impact of knockdown of ncRNA on chemotherapy resistance

Impact of overexpression of ncRNA on chemotherapy resistance

Clinical Information

ncRNA differential expression in
cancer patients vs. healthy people

Down

Number of patients

Not available

Male patients

Not available

Female patients

Not available

Age range and number

Not available

Research information

PMID

28269758

Description

MiR-31 and NDRG3 sensitized HCC cancer cells to adriamycin.

Tissue resource

hepatocellular carcinoma tissues and nontumorous liver tissues

human hepatocellular carcinoma cell lines HepG2

human hepatocellular carcinoma cell lines Hep3B

human hepatocellular carcinoma cell lines 7402

human hepatocellular carcinoma cell lines Huh7

normal liver cell lines LO2

Experiment

qRT-PCR,Western blot

Institute

Weifang Hospital of Traditional Chinese Medicine

American Type Culture Collection

Country

China

USA

Continent

Asia

Amercia

Institutes for Systems Genetics, West China Hospital
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