Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA name
CASC2
Specific or universal ncRNAs
Universal ncRNAs
Class
Long noncoding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factors
Not available
Downstream target
miR-24/caspase-8 and miR-221/caspase-3
Cancer name
Hepatocellular Carcinoma
Cancer site
qRT-PCR,Dual-Luciferase reporter assay
Treatment type
Chemotherapy
Drug
None
Impact of wild-type ncRNA on chemotherapy resistance
Impact of knockdown of ncRNA on chemotherapy resistance
Impact of overexpression of ncRNA on chemotherapy resistance
ncRNA differential expression in
cancer
patients vs. healthy people
Down
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
PMID
Description
These outcomes foreboded that CASC2 could be a novel therapeutic target for further study of HCC-related diseases
Tissue resource
paired hepatocellular carcinoma tissues and adjacent non-cancerous samples
hepatocellular carcinoma cell lines Huh-7
Experiment
None
Institute
the Third Xiangya Hospital, Central South University
China Center for Type Culture Collection
Country
China
China
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.