Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA
hsa-miR-30e-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factor
Not available
Downstream target
PTPN13
Differential expression in
recurrence vs. nonrecurrence
Not available
Cancer name
Lung Adenocarcinoma
Alias
Lung Cancer
Cancer site
Lung
Recurrence type
Recurrence
Overall survival rate of patients with
high ncRNA expression
Down
ncRNA differential expression in
cancer
patients vs. health people
Up
Number of patients
78
Male patients
51
Female patients
27
Age range and number
46(<60)+32(>=60)
Recurrence patients
Not available
Recurrence patients male:female
Not available
Recurrence patients age range
Not available
Recurrence mean age
Not available
Sites of recurrence
Not available
Patients without recurrence
Not available
Patients without recurrence male:female
Patients without recurrence age range
Not available
Patients without recurrence mean age
Not available
PMID
Description
Our findings suggest that miR-30e could function as an oncogene in LAC via targeting PTPN13 and act as a potential therapeutic target for treating LAC.
Tissue resource
lung adenocarcinoma cell lines NCIH1975
lung adenocarcinoma cell lines NCI-H522
lung adenocarcinoma cell lines NCI-H1993
lung adenocarcinoma cell lines NCI-H2087
lung adenocarcinoma cell lines NCI-H2085
lung adenocarcinoma cell lines NCI-H23
lung adenocarcinoma cell lines NCI-2228
lung adenocarcinoma cell lines A549
lung adenocarcinoma cell lines BEAS-2B
lung adenocarcinoma and corresponding adjacent normal tissues
Experiment
qRT-PCR,Western blot
Institute
the Shanghai Cell Bank of Chinese Academy of Science
the Third Affiliated Hospital of Kunming Medical University
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.