Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA
hsa-miR-186-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Prognosis
Upstream regulatory factor
Not available
Downstream target
Not available
Differential expression in
recurrence vs. nonrecurrence
Not available
Cancer name
Gastrointestinal Stromal Tumors
Alias
Soft Tissue Sarcoma
Cancer site
Stomach
Recurrence type
Metastatic Recurrence
Overall survival rate of patients with
high ncRNA expression
Up
ncRNA differential expression in
cancer
patients vs. health people
Not available
Number of patients
100
Male patients
44
Female patients
56
Age range and number
56(<=65)+44(>65)
Recurrence patients
Not available
Recurrence patients male:female
Not available
Recurrence patients age range
Not available
Recurrence mean age
Not available
Sites of recurrence
Not available
Patients without recurrence
Not available
Patients without recurrence male:female
Patients without recurrence age range
Not available
Patients without recurrence mean age
Not available
PMID
Description
These results suggest that the downregulation of miR-186 is involved in the metastatic recurrence of GISTs, and that miR-186 levels could potentially be a predictive biomarker for clinical outcome.
Tissue resource
gastrointestinal stromal tumors cell lines GIST‑T1
gastrointestinal stromal tumors specimens
gastrointestinal stromal tumors cell lines GIST‑T1
gastrointestinal stromal tumors specimens
Experiment
qRT-PCR,Microarray analysis
Institute
the Sapporo Medical University Hospital
the Sapporo Medical University Hospital
Country
Japan
Japan
Continent
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.