Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA
SNHG4
Specific or universal ncRNAs
Specific ncRNAs
Class
Long non-coding RNA
Biomarker
No
Biomarker application
Upstream regulatory factor
Not available
Downstream target
miR-224-3p
Differential expression in
recurrence vs. nonrecurrence
Not available
Cancer name
Osteosarcoma
Alias
Bone Cancer
Cancer site
Bone, Articular Cartilage
Recurrence type
Recurrence
Overall survival rate of patients with
high ncRNA expression
Down
ncRNA differential expression in
cancer
patients vs. health people
Up
Number of patients
Not available
Male patients
Not available
Female patients
Not available
Age range and number
Not available
Recurrence patients
Not available
Recurrence patients male:female
Not available
Recurrence patients age range
Not available
Recurrence mean age
Not available
Sites of recurrence
Not available
Patients without recurrence
Not available
Patients without recurrence male:female
Patients without recurrence age range
Not available
Patients without recurrence mean age
Not available
PMID
Description
LncRNA SNHG4 promoted tumour growth by sponging miR-224-3p and represented a poor prognostic factor in patients with osteosarcoma.
Tissue resource
Osteosarcoma cell lines U-2OS
Osteosarcoma cell lines Saos-2
Osteosarcoma cell lines SW-1353
Osteosarcoma cell lines 143B
Osteosarcoma cell lines HOS
Osteosarcoma cell lines MG-63
osteosarcoma and adjacent normal tissues
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
Renji Hospital, Shanghai Jiao Tong University School of Medicine
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.