HOTTIP

ncRNA information

ncRNA

HOTTIP

Specific or universal ncRNAs

Universal ncRNAs

Class

Long non-coding RNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factor

Not available

Downstream target

Not available

Differential expression in
recurrence vs. nonrecurrence

Not available

Cancer information

Cancer name

Hepatocellular Carcinoma

Alias

Liver Cancer

Cancer site

Liver

Recurrence type

Recurrence

Clinical information

Overall survival rate of patients with
high ncRNA expression

Down

ncRNA differential expression in
cancer patients vs. health people

Not available

Number of patients

155

Male patients

141

Female patients

14

Age range and number

81(<=50)+74(>50)


Recurrence patients

Not available

Recurrence patients male:female

Not available

Recurrence patients age range

Not available

Recurrence mean age

Not available

Sites of recurrence

Not available


Patients without recurrence

Not available

Patients without recurrence male:female

Patients without recurrence age range

Not available

Patients without recurrence mean age

Not available

Research information

PMID

Description

The high expression level of HOTTIP in HCC could serve as a candidate biomarker for predicting poor prognosis in HCC patients underwent liver transplant therapy.

Tissue resource

the metastatic human HCC cell lines MHCC97L

the metastatic human HCC cell lines HCCLM3

liver cancer cell lines Hep3B

liver cancer cell lines PLC/PRF/5

liver cancer cell lines SK-Hep1

liver cancer cell lines Bel-7402

liver cancer cell lines HepG2

liver cancer cell lines Huh-7

liver cancer cell lines SMMC-7721

normal liver cell lines LO2

human hepatocellular carcinoma tissues

the metastatic human HCC cell lines MHCC97H

Experiment

qRT-PCR


Institute

American Type Culture Collection

the First Affiliated Hospital, Zhejiang University School of Medicine

Country

USA

China

Continent

North American

Asia