Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA
hsa-miR-150-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Prognosis/Treatment
Upstream regulatory factor
Not available
Downstream target
c-Myb/Slug
Differential expression in
recurrence vs. nonrecurrence
Not available
Cancer name
Ovarian Cancer
Alias
Cancer site
Ovary
Recurrence type
Recurrence
Overall survival rate of patients with
high ncRNA expression
Down
ncRNA differential expression in
cancer
patients vs. health people
Not available
Number of patients
22
Male patients
Not available
Female patients
Not available
Age range and number
Not available
Recurrence patients
Not available
Recurrence patients male:female
Not available
Recurrence patients age range
Not available
Recurrence mean age
Not available
Sites of recurrence
Not available
Patients without recurrence
Not available
Patients without recurrence male:female
Patients without recurrence age range
Not available
Patients without recurrence mean age
Not available
PMID
Description
MiR-150-5p upregulation mediates the progression of recurrent OvCa by targeting the c-Myb/Slug pathway. Inhibition of miR-150-5p may serve as a new therapeutic strategy for preventing recurrence of OvCa.
Tissue resource
the human ovarian cancer cell lines IGROV1
the human ovarian cancer cell lines TOV21G
the human ovarian cancer cell lines A2780/CP70
the human ovarian cancer cell lines A2780
the human ovarian cancer cell lines BG1
the human ovarian cancer cell lines SKOV3
ovarian cancer tissues
Tissues from ovarian cancer
human OvCa cell lines SKOV3
human OvCa cell lines BG1
human OvCa cell lines A2780
human OvCa cell lines A2780/CP70
human OvCa cell lines TOV21G
human OvCa cell lines IGROV1
Experiment
qRT-PCR,Western blot,Luciferase reporter assay
Institute
the National Cheng Kung University Hospital
National Cheng Kung University Hospital
National Cheng Kung University Hospital
National Cheng Kung University Hospital
National Cheng Kung University Hospital
National Cheng Kung University Hospital
National Cheng Kung University Hospital
National Cheng Kung University Hospital
Country
China
China
China
China
China
China
China
China
Continent
Asia
Asia
Asia
Asia
Asia
Asia
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.