Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA
has-miR-21-5p
Specific or universal ncRNAs
Specific ncRNAs
Class
MicroRNA
Biomarker
Yes
Biomarker application
Prognosis
Upstream regulatory factor
IL-6/JAK2/STAT3
Downstream target
Not available
Differential expression in
recurrence vs. nonrecurrence
Up
Cancer name
Hepatocellular Carcinoma
Alias
Liver Cancer
Cancer site
Liver
Recurrence type
Recurrence
Overall survival rate of patients with
high ncRNA expression
Down
ncRNA differential expression in
cancer
patients vs. health people
Up
Number of patients
50
Male patients
40
Female patients
10
Age range and number
16(<=50)+34(>50)
Recurrence patients
16
Recurrence patients male:female
0.54375
Recurrence patients age range
58.38”Ą11.26
Recurrence mean age
Not available
Sites of recurrence
Not available
Patients without recurrence
34
Patients without recurrence male:female
Patients without recurrence age range
Not available
Patients without recurrence mean age
Not available
PMID
Description
MiRNA-21 expression, induced by IL-6/JAK2/STAT3 signaling pathway, was increased in the early recurrence of HCC patients and indicated poor prognosis.
Tissue resource
hepatocellular carcinoma tumor and adjacent nontumor tissue
Experiment
qRT-PCR
Institute
the Affiliated Hospital of Qingdao University
Country
China
Continent
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.