Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.
ncRNA
LNAPPCC
Specific or universal ncRNAs
Specific ncRNAs
Class
Long non-coding RNA
Biomarker
Yes
Biomarker application
Treatment
Upstream regulatory factor
Not available
Downstream target
PCDH7
Differential expression in
recurrence vs. nonrecurrence
Up
Cancer name
Colon cancer
Alias
Colon cancer
Cancer site
Colon, Rectum, and Anus
Recurrence type
Recurrence
Overall survival rate of patients with
high ncRNA expression
Down
ncRNA differential expression in
cancer
patients vs. health people
Not available
Number of patients
62
Male patients
29
Female patients
33
Age range and number
Not available
Recurrence patients
Not available
Recurrence patients male:female
Not available
Recurrence patients age range
Not available
Recurrence mean age
Not available
Sites of recurrence
Not available
Patients without recurrence
Not available
Patients without recurrence male:female
Patients without recurrence age range
Not available
Patients without recurrence mean age
Not available
PMID
Description
Targeting LNAPPCC/EZH2/PCDH7/ERK/c-FOS signaling axis represents a potential therapeutic strategy for colon cancer.
Tissue resource
colon cancer tissues and matched adjacent normal tissues
normal human colon mucosal epithelial cell lines NCM460
colon cancer cell lines HT-29
colon cancer cell lines SW620
colon cancer cell lines HCT-15
colon cancer cell lines HCT116
Experiment
qRT-PCR,Western blot
Institute
Hainan General Hospital
Cell Bank of Type Culture Collection of Chinese Academy of Sciences
Cell Bank of Type Culture Collection of Chinese Academy of Sciences
Cell Bank of Type Culture Collection of Chinese Academy of Sciences
Cell Bank of Type Culture Collection of Chinese Academy of Sciences
Country
China
China
China
China
China
Continent
Asia
Asia
Asia
Asia
Asia
Institutes for Systems Genetics, West China Hospital
Copyright @ 2022 ISG. All Rights Reserved.