LNAPPCC

ncRNA information

ncRNA

LNAPPCC

Specific or universal ncRNAs

Specific ncRNAs

Class

Long non-coding RNA

Biomarker

Yes

Biomarker application

Treatment

Upstream regulatory factor

Not available

Downstream target

PCDH7

Differential expression in
recurrence vs. nonrecurrence

Up

Cancer information

Cancer name

Colon cancer

Alias

Colon cancer

Cancer site

Colon, Rectum, and Anus

Recurrence type

Recurrence

Clinical information

Overall survival rate of patients with
high ncRNA expression

Down

ncRNA differential expression in
cancer patients vs. health people

Not available

Number of patients

62

Male patients

29

Female patients

33

Age range and number

Not available


Recurrence patients

Not available

Recurrence patients male:female

Not available

Recurrence patients age range

Not available

Recurrence mean age

Not available

Sites of recurrence

Not available


Patients without recurrence

Not available

Patients without recurrence male:female

Patients without recurrence age range

Not available

Patients without recurrence mean age

Not available

Research information

PMID

Description

Targeting LNAPPCC/EZH2/PCDH7/ERK/c-FOS signaling axis represents a potential therapeutic strategy for colon cancer.

Tissue resource

colon cancer tissues and matched adjacent normal tissues

normal human colon mucosal epithelial cell lines NCM460

colon cancer cell lines HT-29

colon cancer cell lines SW620

colon cancer cell lines HCT-15

colon cancer cell lines HCT116

Experiment

qRT-PCR,Western blot


Institute

Hainan General Hospital

Cell Bank of Type Culture Collection of Chinese Academy of Sciences

Cell Bank of Type Culture Collection of Chinese Academy of Sciences

Cell Bank of Type Culture Collection of Chinese Academy of Sciences

Cell Bank of Type Culture Collection of Chinese Academy of Sciences

Country

China

China

China

China

China

Continent

Asia

Asia

Asia

Asia

Asia