hsa-miR-17-5p

ncRNA information

ncRNA

hsa-miR-17-5p

Specific or universal ncRNAs

Universal ncRNAs

Class

MicroRNA

Biomarker

Yes

Biomarker application

Prognosis

Upstream regulatory factor

Not available

Downstream target

Not available

Differential expression in
recurrence vs. nonrecurrence

Not available

Cancer information

Cancer name

Head And Neck Squamous Cell Carcinoma

Alias

Head and Neck Cancers

Cancer site

Head, Neck

Recurrence type

Recurrence

Clinical information

Overall survival rate of patients with
high ncRNA expression

Up

ncRNA differential expression in
cancer patients vs. health people

Down

Number of patients

64

Male patients

61

Female patients

3

Age range and number

Not available


Recurrence patients

Not available

Recurrence patients male:female

Not available

Recurrence patients age range

Not available

Recurrence mean age

Not available

Sites of recurrence

Not available


Patients without recurrence

Not available

Patients without recurrence male:female

Patients without recurrence age range

Not available

Patients without recurrence mean age

Not available

Research information

PMID

Description

These findings suggest that miR-17-5p might act as a tumor promoter and prognostic factor for recurrence in HNSCC patients

Tissue resource

tissues from laryngeal cancer and hypopharyngeal cancer and tissues obtained from patients diagnosed with vocal cord polyps

head and neck squamous cell carcinoma cell lines AMC-HN8

head and neck squamous cell carcinoma cell lines Tu686

head and neck squamous cell carcinoma cell lines FaDu

head and neck squamous cell carcinoma cell lines Detroit562

Experiment

qRT-PCR,Western blot,Dual-luciferase reporter assay


Institute

Eye & ENT Hospital, Fudan University

Eye & ENT Hospital, Fudan University

Central South University

Cell Bank of the Shanghai Institute of Cells, Chinese Academy of Science

Cell Bank of the Shanghai Institute of Cells, Chinese Academy of Science

Country

China

China

China

China

China

Continent

Asia

Asia

Asia

Asia

Asia