Amyotrophic Lateral Sclerosis Functional Rating Scale

Content
Basic information

Name: Amyotrophic Lateral Sclerosis Functional Rating Scale

Abbreviation: ALSFRS

Versions: 3

Synonyms: 147

Description: The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) is an instrument for evaluating the functional status of patients with Amyotrophic Lateral Sclerosis. It can be used to monitor functional change in a patient over time. Measures: (1) speech (2) salivation (3) swallowing (4) handwriting (5) cutting food and handling utensils (with or without gastrostomy) (6) dressing and hygiene (7) turning in bed and adjusting bed clothes (8) walking (9) climbing stairs (10) breathing (, https://www.sralab.org/sites/default/files/2017-07/PMandR_ALSRatingScale033111.pdf)

Reference: de Jongh AD, van den Berg LH, van Eijk RPA. Reconsidering the revised amyotrophic lateral sclerosis functional rating scale for ALS clinical trials. Journal of neurology, neurosurgery, and psychiatry. 2021 May. PMID: 33229452. DOI: 10.1136/jnnp-2020-325253

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Temporal prevalence

Distribution in different diseases

Distribution in different versions

# version trials
1 Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised 263
2 Amyotrophic Lateral Sclerosis Functional Rating Scale 57
3 Korean Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised 1
Complementary instruments

# instruments trials
1 Amyotrophic Lateral Sclerosis Assessment Questionnaire 46
2 Hand Held Dynamometry 32
3 Edinburgh Cognitive and Behavioral Amyotrophic Lateral Sclerosis Screen 18
4 EQ-5D 17
5 Manual Muscle Testing 16
6 Amyotrophic Lateral Sclerosis Specific Quality of Life 16
7 Medical Research Council Scale 12
8 Amyotrophic Lateral Sclerosis Cognitive Behavioral Screen 11
9 Visual Analogue Scale 10
10 Combined Assessment of Function and Survival 10
11 Short Form Health Survey 9
12 Clinical Global Impression 8
13 Norris Scale 8
14 Hospital Anxiety and Depression Scale 7
15 King's Staging Scale 6
16 Beck Depression Inventory 5
17 Fatigue Severity Scale 5
18 Accurate Test of Limb Isometric Strength 5
19 Neuropsychiatric Inventory 4
20 Epworth Sleepiness Scale 4
21 World Health Organization Quality of Life 4
22 Columbia Suicide Severity Rating Scale 4
23 Time Up and Go Test 4
24 Patient-Reported Outcomes Measurement Information System 4
25 Minute Walk Test 4
26 EQ-VAS 4
27 Ashworth Spasticity Scale 4
28 Center for Neurologic Study-Bulbar Function Scale 4
29 Eating Assessment Tool-10 Questionnaire 4
30 Amyotrophic Lateral Sclerosis Depression Inventory 4
31 Rasch-Built Overall Amyotrophic Lateral Sclerosis Disability Scale 4
32 Dyspnea-ALS-Scale 4
33 Caregiver Burden Inventory 3
34 Patient Global Impression 3
35 McGill Quality of Life Questionnaire 3
36 Functional Oral Intake Scale 3
37 Swallowing Quality of Life Questionnaire 3
38 Sensory Examinations 3
39 Council of Nutrition Appetite Questionnaire 3
40 Appel Amyotrophic Lateral Sclerosis Rating Scale 3
41 Severe Respiratory Insufficiency Questionnaire 3
42 Upper Motor Neuron Scale 3
43 Motor Unit Number Index 3
44 Apathy Evaluation Scale 2
45 Frontal Behavioral Inventory 2
46 Quality of Life Questionnaire 2
47 Unified Parkinson's Disease Rating Scale 2
48 Montreal Cognitive Assessment 2
49 Barthel Index 2
50 Patient Health Questionnaire 2
51 Generalized Anxiety Disorder Scale-7 2
52 Meter Walk Test 2
53 Numeric Rating Scale 2
54 Penetration-Aspiration Scale 2
55 Acceptability of Intervention Measure 2
56 Feasibility of Intervention Measure 2
57 Maximum Voluntary Isometric Contraction 2
58 Adolescent Anger Rating Scale 2
59 Muscle Strength Assessment 2
60 EasyOne Spirometer System 2
61 Investigator Global Assessment 2
62 Micro Medical Respiratory Pressure Meter 2
63 Patient Global Assessment 2
64 Schedule for the Evaluation of Individual Quality of Life 2
65 Patient Satisfaction Questionnaire 2
66 Borg Rating Scale of Perceived Exertion 2
67 Mann Assessment of Swallowing Ability 2
68 Mini-Mental State Examination 1
69 Zarit Burden Interview 1
70 Depression Rating Scale 1
71 Montgomery-Åsberg Depression Rating Scale 1
72 Profile of Mood States Questionnaire 1
73 Pittsburgh Sleep Quality Index 1
74 Frontal Assessment Battery 1
75 Verbal Fluency Test 1
76 Berg Balance Scale 1
77 Goal Attainment Scale 1
78 Schwab and England Activities on Daily Living Scale 1
79 Center for Neurologic Study-Lability Scale 1
80 Caregiver Burden Scale 1
81 Sit to Stand Test 1
82 Addenbrooke's Cognitive Examination 1
83 Self-Compassion Scale 1
84 Neurologic Study Emotional Lability Scale 1
85 Client Satisfaction Questionnaire 1
86 Brief Pain Inventory 1
87 Preparedness for Caregiving Scale 1
88 Self-Efficacy for Managing Chronic Disease Scale 1
89 Quality of Life in Neurological Disorders 1
90 Karolinska Sleepiness Scale 1
91 Working Alliance Inventory 1
92 Ashworth Scale 1
93 Nine-Hole Peg Test 1
94 Barium Swallow Impairment Profile 1
95 Iowa Oral Performance Instrument 1
96 Burden Scale for Family Caregivers 1
97 Functional Independence Measure 1
98 Assessment of Quality of Life Questionnaire 1
99 Amyotrophic Lateral Sclerosis Health Index 1
100 Spastic Paraplegia Rating Scale 1
101 Communicative Effectiveness Survey 1
102 Intervention Appropriateness Measure 1
103 Apnea Hypopnea Index 1
104 McGill Pain Questionnaire 1
105 Fatigue Impact Scale 1
106 Checklist Individual Strength Questionnaire 1
107 Motor Unit Number Estimation 1
108 Timed 25-Foot Walk Test 1
109 Neuropathic Pain Scale 1
110 Ellis Reflex Scale 1
111 Frontotemporal Dementia Assessment 1
112 Own Designed Questionaire 1
113 Drooling Rating Scale 1
114 Social Security Death Index 1
115 Solids Swallowing Test 1
116 Water Swallowing Test 1
117 EMG Scale 1
118 3-ounce Water Swallow Test 1
119 Quantitative Myasthenia Gravis Scale 1
120 Sydney Swallow Questionnaire 1
121 Gross Motor Function Measure 1
122 Beck Inventory Scale 1
123 Iowa Oral Pressure Instrument 1
124 Patient Activities of Daily Living for Amyotrophic Lateral Sclerosis Survey 1
125 Quantitative Hand Muscle Testing 1
126 Sniff Nasal Inspiratory Pressure Test 1
127 Patient Reported Experience Measures 1
128 Edinburgh Cognitive Assessment 1
129 Langer Mindfulness Scale 1
130 Muscle Cramp Questionnaire 1
131 Dysphagia Severity Rating Scale 1
132 Supine Borg Category Ratio 10 Scale 1
133 Batterie d'Evaluation Clinique de la Dysarthrie 1
134 Speech and Language Battery 1
135 Borg Category-Ratio Scale 1
136 Ulmer Eating Habits Questionnaire 1
137 Hammersmith Functional Motor Scale Expanded 1
138 Muscle Strength Scale 1
139 Adherence to Refills and Medications Scale 1
140 Exercise Adherence Rating Scale 1
141 Interpersonal Processes of Care 1
142 Medical Outcomes Study General Adherence 1
143 Single Item Literacy Screener 1
144 Ulm Nutrition Questionnaire 1
145 Beck Scale 1
146 Spontaneous Swallowing Task 1
147 Self-designed Questionnaire 1
148 Cramp Pain Scale 1
149 Muscle Cramp Scale 1
150 Weekly Cramp Diary 1
151 Communicative Participation Item Bank 1
152 Psychosocial Impact of Assistive Devices Scale 1
153 Amyotrophic Lateral Sclerosis Treatment Questionnaire 1
154 Digital Outcome Assessment 1
155 Penn Upper Motor Neuron Score 1
156 Revised Upper Limb Module 1
157 Calgary Sleep Apnoea Quality of Life Index 1
158 Caregiver Semi-structured Interview 1
159 Caregiving Distress Scale 1
160 Dyspnea-12 Questionnaire 1
161 General Satisfaction Subscale 1
162 Neurological Fatigue Index for MND 1
163 Patient Level Information and Costing System 1
164 Dysphagia Outcome and Severity Scale 1
165 Questionnaire on Attitudes Toward PEG Tube Feeding and Insertion Procedure 1
166 Yale Pharyngeal Residue Severity Rating Scale 1
167 Vulvovaginal Symptoms Questionnaire 1