Basic information
Biomarker: IRAK1
Histology type: endometrial carcinoma
Cohort characteristics
Country: China
Region: Beijing
Followed up time :
Subgroup 1 name : Endometrial cancer
Subgroup 1 number: 89
Subgroup 2 name: Adjacent non-tumorous tissue
Subgroup 2 number: 89
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 178 | EC | 89 | adjacent non-tumorous tissue | 89 |
Sample information
Conclusion: These collective data indicated that IRAK1 overexpression promotes EC tumorigenesis by activating mitotic cell cycle and cell division pathways, and IRAK1 may serve as a promising therapeutic strategy for EC.
Sample method: qRT-PCR/western blot/Immunohistochemistry
Expression pattern : overexpression
Expression elevation: The specimens were graded into IRAK1-high-expression group (>20% of tumor cells showed positive stain) and IRAK1-low-expression group (< 20% of the tumor cells showed positive stain).
Disease information
Statictics: Median;Range
Cohort age: 59;27-71
Related information
UniProt Link:
Molecular function from UniProt:
